Use of crosslinkers to inactivate dentin MMPs
نویسندگان
چکیده
منابع مشابه
Role of dentin MMPs in caries progression and bond stability.
Dentin can be described as a biological composite with collagen matrix embedded with nanosized hydroxyapatite mineral crystallites. Matrix metalloproteinases (MMPs) and cysteine cathepsins are families of endopeptidases. Enzymes of both families are present in dentin and collectively capable of degrading virtually all extracellular matrix components. This review describes these enzymes and thei...
متن کاملMorphological effects of MMPs inhibitors on the dentin bonding.
Matrix metalloproteinases (MMPs) have been studied extensively, and MMP inhibitors have been used as dental pretreatment agents prior to dentin bonding because they reduce collagen fiber degradation and improve bonding strength. However, morphologic characteristics of the collagen network after etching and of the post-adhesive dentin hybrid layers (DHL) after MMP inhibitors pretreatment have no...
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OBJECTIVES The work has the objective to analyze the literature on the degradation of the adhesive interface. In particular the study is focused on the role of the metalloproteinase in the hydrolytic degradation of collagen matrix in the bonded interface. The survey will concern also the latest innovations to improve and increase the link between dentin and the restorative materials through the...
متن کاملMatrix Metalloproteinases (mmps) in the Dentin-pulp Complex of Healthy and Carious Teeth
The dentin-pulp complex comprises mineralized dentin and the vital soft tissues encased inside dentin, i.e. odontoblasts and pulp tissue. During caries progression, the dentinal minerals are dissolved and eventually the collagenous organic matrix is degraded. However, the exact mechanisms and enzymes responsible for the organic matrix breakdown remain unknown. Matrix metalloproteinases (MMPs), ...
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Microtensile bond strength of clearfil SE bond to caries-affected dentin and normal dentin Dr. A. Ghasemi* - Dr. M. Bargrizan** - Dr. M. Mahmoodi*** *- Assistant Professor of Operative Dentistry Dept. - Faculty of Dentistry – Shaheed Beheshti University of Medical Sciences. **- Assistant Professor of Pedodontics Dept. - Faculty of Dentistry – Shaheed Beheshti University of Medical Sciences. ***...
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ژورنال
عنوان ژورنال: Dental Materials
سال: 2016
ISSN: 0109-5641
DOI: 10.1016/j.dental.2015.12.012